Good clinical response to methotrexate treatment in a patient with fibroblastic rheumatism
Identifieur interne : 001718 ( Main/Exploration ); précédent : 001717; suivant : 001719Good clinical response to methotrexate treatment in a patient with fibroblastic rheumatism
Auteurs : Juliane Aline Paupitz [Brésil] ; Jozélio Freire De Carvalho [Brésil]Source :
- Rheumatology International [ 0172-8172 ] ; 2012-06-01.
English descriptors
Abstract
Abstract: Fibroblastic rheumatism (FR) is a rare disease first described by Chaouat (in Rev Rhum Mal Osteoartic 47:345–351, 1980) and is characterized by a combination of rheumatologic and dermatological manifestations. Rheumatologic features are symmetrical polyarthralgias with joint stiffness, associated with cutaneous nodules and sclerodactyly. Histology shows an increased number of fibroblasts and a marked dermal fibrosis. A large number of treatments have been tried, but all of them have shown an unpredictable effect on FR. We report a Brazilian case of FR showing a good clinical response to methotrexate treatment. This drug may be considered an effective treatment in FR.
Url:
DOI: 10.1007/s00296-010-1433-2
Affiliations:
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